Entries in Anticoagulant (2)


Study: New Drug May Prevent Stroke Better Than Aspirin

Photo Courtesy - Getty Images(ONTARIO, Canada) -- Patients at risk for strokes from blood clots who take aspirin because they can't take strong blood thinning drugs like warfarin may benefit significantly from a new drug, according to a new study presented at an American Stroke Association meeting in Canada.

The study's authors compared a new blood thinning drug, apixaban, to aspirin in 5,600 patients with atrial fibrillation -- an abnormal heart beat that can increase a person’s risk of stroke from blood clots -- who could not take warfarin.  Over a period of about one year, they found that 1.6 percent of those taking apixaban suffered a stroke compared to 3.6 percent of those taking aspirin.

The findings were considered so significant that the study was stopped early.

Additionally, apixaban was just as safe as aspirin in these patients, with major bleeding events in each group being 1.4 percent and 1.2 percent for apixaban and aspirin, respectively.

Copyright 2011 ABC News Radio


FDA Approves New Blood Thinner

Photo Courtesy - Getty Images(WASHINGTON) -- The U.S. Food and Drug Administration Tuesday approved a new blood thinner called Pradaxa, intended to prevent strokes and blood clots for people with irregular heart rhythms.

At least one trial has found Pradaxa to be more effective than the blockbuster blood thinner Coumadin (warfarin).

"Unlike warfarin, which requires patients to undergo periodic monitoring with blood tests, such monitoring in not necessary for Pradaxa," said Norman Stockbridge, M.D., Ph.D., director of the Division of Cardiovascular and Renal Products in the FDA's Center for Drug Evaluation and Research.

The FDA warns that just as with other anti-clotting drugs, patients taking Pradaxa may be at risk for bleeding, including life-threatening and fatal bleeding.  Stomach pain, nausea, heartburn and bloating are also among the reported side effects.

Pradaxa is manufactured by Boehringer Ingelheim Pharmaceuticals Inc. of Ridgefield, Connecticut.

Copyright 2010 ABC News Radio

ABC News Radio