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Entries in Brown Fat (2)

Sunday
May062012

Fat Research May Lead to New Treatments for Obesity

(NEW YORK) -- A recent study revealing that scientists have found a way to turn white, bad fat into brown, good fat, may lead to new obesity treatments, Health Day reports.
 
White fat stores energy, causing weight gain, while brown fat burns energy, preventing obesity, says the health news service. The fat caused by white fat cells that accumulates around organs in the belly has been linked to an increased risk of heart disease and diabetes, the researchers said. During the study, they found a way to make white fat take on the characteristics of brown fat by blocking vitamin A metabolism in white fat, according to Health Day.

These findings could lead to new ways to treat obesity and its complications. The study was published on Sunday, May 6 in the online edition of the journal Nature Medicine.

Copyright 2012 ABC News Radio

Tuesday
Jan242012

Why Brown Fat Is No Obesity Cure…Yet

Jupiterimages/Thinkstock(WASHINGTON) -- If you were asked to envision a dream solution for the obesity epidemic, you couldn’t do much better than the concept of calorie-burning fat -- in other words, “good” fat in the body that essentially burns calories.

So it may come as little surprise that headlines about brown fat are getting a fair bit of attention.

The bad news is that what we know at the moment is not going to help you get any slimmer — at least not in the foreseeable future.

True, brown fat sounds great as a concept. We know that it exists in the bodies of some mammals, and its main function is to produce heat in cold conditions. It’s a key survival mechanism for some animals living in colder environments that allows them to produce body heat without having to deplete precious energy stores, which happens when muscles shiver in the cold.

In order to produce this heat, brown fat burns calories. This differentiates it from the white fat with which all of us are familiar -- and which tends to sit in unsightly lumps around our bellies, butts and thighs.

Until recently, brown fat was thought to play a metabolic role only in small mammals and infants; only in recent years has its presence and metabolic role in adult humans garnered serious interest.

So the excitement is understandable. After all, if more of us humans could somehow offset some of our white fat with brown fat, we might not have such a huge problem with obesity.

Unfortunately, it’s not that simple -- and the study released Tuesday in the Journal of Clinical Investigation may not do much to advance what we know about how brown fat is relevant to humans.

In this study, Canadian researchers exposed healthy men ranging from 23 to 42 years of age, to cold temperatures. Researchers used medical scans to detect evidence of the activity of brown fat in the body. What they found was that the amount of calories the men burned while at rest did increase when they were exposed to cold. The men who were thought to have more brown fat actually shivered less -- lending some credence to the idea that their brown fat was kicking in to burn calories.

This finding was tempered by the fact that the study only included six participants and that there was no control group with whom to compare the men who were exposed to the chilly temperatures. Additionally, the study was not designed to see the brown fat directly, only to measure its activity indirectly. So if you’re looking for proof of the existence of brown fat in humans, you might need to wait a little longer.

“The ultimate question is, ‘how big a factor is this when it comes to weight?’” said Dr. David Katz, founding director of Yale University’s Prevention Research Center in New Haven, Conn. “As best I can tell, we can’t answer that questions yet; we’re looking at studies that are very small.”

Copyright 2012 ABC News Radio







ABC News Radio