Entries in Guillain-Barré (2)


H1N1 Flu Vaccine Not Linked to Risk of Paralysis, Researchers Say

Jeffrey Hamilton/Thinkstock(ROTTERDAM, Netherlands) -- Guillain-Barré syndrome is a rare condition in which a person’s immune system attacks nerve cells, causing muscle weakness and sometimes paralysis.  

Although in the past there has been some concern that flu vaccines may increase the risk of this condition, a recent study published in the British Medical Journal found that people in five European countries who received the H1N1 vaccine in 2009 were at no greater risk of Guillain-Barré as those who did not receive the shot.  

Furthermore, the authors from Erasmus University Medical Center estimate, based on their results, that the actual risk of Guillain-Barré syndrome is less than three cases for every one million individuals protected by the vaccination.  

Authors of the accompanying editorial write that although the H1N1 stand-alone vaccine is no longer being used, “data on their safety are relevant to current clinical practice because the H1N1 strain in the pandemic vaccine has been incorporated into the currently recommended trivalent seasonal vaccine.”

Copyright 2011 ABC News Radio


NFL Quarterback Diagnosed with Guillain-Barré Syndrome

James D. Smith/WireImage(ATLANTA) -- Former quarterback Danny Wuerffel has been diagnosed with Guillain-Barré syndrome, a rare autoimmune disorder that causes paralysis. Wuerffel, who lives in Decatur, Ga., noticed he was losing sensation in his legs and strength in his arms shortly after he battled a stomach virus June 4. It's thought that his immune system started to attack the nerves that control movement and sensation, mistaking them for the virus.

Wuerffel's strength is currently half of what it was, according to his wife, Jessica.

"He's hanging in there," said Jessica, who was taking their three young kids to the beach for a distraction. "It's a distressing situation but, to be honest, his faith is strong."

Guillain-Barré syndrome affects about one in 100,000 people, usually striking in the days or weeks following a viral infection, according to the National Institutes of Neurological Disorders and Stroke. Surgery and vaccinations can also trigger the disorder. But it's unclear why some people are affected while others are not.

"It's like a bolt of lightning that kind of comes out of the blue," said Dr. James Caress, associate professor of neurology at Wake Forest University Baptist Medical Center in Winston Salem, N.C.

Most people with Guillain-Barré reach their weakest point within two to four weeks after symptoms first appear. In severe cases, the disorder can attack the nerves that control breathing muscles, such that patients need artificial ventilators and feeding tubes to survive, Caress said.

Wuerffel is not completely paralyzed, but has been advised by his doctors to stay immobile during his recovery, his wife said. But it's unclear how long that recovery will take.

Treatments for Guillain-Barré, such as plasma exchange and intravenous immunoglobulins, are aimed at ridding the body of the dangerous antibodies attacking the nerves and replacing them with healthy antibodies from donors. But while treatments can the accelerate recovery, they may not influence how weak the person gets before regaining his or her strength.

Recovery time runs from a few weeks to a few years. But about 30 percent of patients still have some degree of weakness after three years, according to the National Institutes of Neurological Disorders and Stroke.

Wuerffel, who won the Heisman Trophy in 1996 while playing for the Florida Gators, was drafted by the New Orleans Saints in 1997. He played for the Green Bay Packers, the Chicago Bears, and the Washington Redskins before retiring from the National Football League in 2002. He now heads up Desire Street Ministries, a Christian charity that serves impoverished communities in New Orleans.

Copyright 2011 ABC News Radio

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