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Entries in Triclosan (2)

Tuesday
Aug142012

Soap Ingredient Triclosan Linked to Muscle Weakness

Altrendo Images/Stockbyte/Thinkstock(DAVIS, Calif.) -- Soap may hold a dirty little secret in the form of a chemical called triclosan.  Used in antiseptic hand soaps, shaving cream, toothpaste, deodorant and other hygiene products, a new study has found the chemical can weaken muscle contraction.

When researchers at the University of California at Davis exposed the individual muscle fibers of fish and mice to triclosan, they found it impaired the normal contraction mechanism.  Both skeletal muscle and cardiac muscle no longer operated normally, and this was true when the mice and fish were tested themselves, or their muscle fibers were examined individually in a test tube.

Mice showed up to a 25 percent reduction in heart function measured within 20 minutes of exposure to the chemical, as well as an 18 percent reduction in grip strength up to 60 minutes after exposure.  Fish that swam in triclosan-tainted water for seven days performed worse on swimming tests than those that did not.

While the evidence for toxicity is largely based on animal studies, some experts have said that it might affect humans too.

"This is an interesting and potentially concerning finding," said Dr. Philip J. Landrigan, dean of global health in the department of preventive medicine at the Mount Sinai School of Medicine in New York City.  "Many synthetic chemicals now known to be toxic to humans were first recognized as toxic in animal studies."

Landrigan said that exposure in the womb is of particular worry.

"Early development is a time of particular vulnerability to toxic chemicals.  Minute exposures at the wrong moment in embryonic or fetal development can have devastating effects.  The great complexity of early human development creates windows of vulnerability, periods of heightened sensitivity to toxic chemicals that exist only in early life and have no counterpart in adulthood," he said.

Adding to the potential worry, previous studies have found that triclosan may alter hormone regulation in laboratory animals, or cause antibiotic resistance.

Not all experts believe the chemical is a problem because in it remains bound to blood proteins, which should in theory diminish its impact on humans.  And manufacturers are adamant that there is no real proof triclosan is dangerous for humans.  They're also quick to point out several recent studies that demonstrated its effectiveness in killing germs.

But some consumer groups and members of Congress have called for a ban on antiseptic soap products.

Both the Food and Drug Administration and the Environmental Protection Agency are currently reviewing the chemical's safety, but the FDA said it didn't have sufficient evidence for a ban.

This latest study was published in the Proceedings of the National Academy of Science.

Copyright 2012 ABC News Radio

Wednesday
Aug242011

FDA Reviewing Antibacterial Chemical Triclosan

Comstock Images/Thinkstock(WASHINGTON) -- Triclosan, an antibacterial chemical found in hundreds of soaps and cleaners, may be getting a dirty reputation.

The chemical has been under review since April 2010, and now the Food and Drug Administration announced that it will extend its assessment of triclosan after several animal studies have shown that the antiseptic may disrupt hormone levels and even cause antibiotic resistance.

The FDA has stated there is not enough evidence to discourage consumers to stay away from products containing triclosan, but the federal organization also noted there is no evidence that the antibacterial provides any more benefit to washing in a household setting than regular soap and water.

Triclosan was originally intended as a hospital surgical scrub to prevent transmission of disease in patients. Today, the chemical is found in thousands of household products.

"It is a valuable product when used in hospitals to inhibit growth of organisms and has been shown to prevent infection in hospitals," said Dr. Stuart Levy, professor of microbiology at Tufts University School of Medicine, who has conducted studies on triclosan's safety in household products.  "But the use of the chemical in household products is not the place it should be used."

In 2001, Levy and other Tufts scientists conducted research that found 75 percent of study participants ages 5 and older had traces of the substance in their urine.

"[Antibacterial products] are now being added to products used in healthy households, even though an added health benefit has not been demonstrated," study authors wrote.  "Scientists are concerned that the antibacterial agents will select bacteria resistant to them and cross-resistant to antibiotics."

But the American Cleaning Institute rejects the dangers, and adds that triclosans benefits all who use the products.

"These products play a beneficial role in the daily hygiene routines of millions of people throughout the U.S. and worldwide," a spokesperson for the American Cleaning Institute wrote in a statement.  "They have been and are used safely and effectively in homes, hospitals and workplaces every single day."

"Bottom line, where is the benefit?" Levy asked rhetorically.  "It has much more harm than benefit."

Copyright 2011 ABC News Radio







ABC News Radio