Entries in Warfarin (2)


New Drug Busts Blood Clots with Fewer Side Effects

Ingram Publishing/Thinkstock(CHICAGO) -- A new blood thinner offers simpler and safer treatment for pulmonary embolism, a deadly condition in which a lung blood vessel becomes blocked by a blood clot.

Venous blood clots have long been treated with warfarin, a drug fraught with food and drug interactions. On top of keeping a strict diet, patients must comply with frequent blood tests and complex dosing schedules.

But a new study suggests the drug rivaroxaban performs as well as warfarin in treating existing blood clots in the lung with less monitoring and fewer side effects.

“You don’t have to go to the lab to monitor. It’s a fixed dose. It is as effective, and it looks safer,” said study author Dr. Harry Bueller, professor of vascular medicine at the American Medical Center in Amsterdam.

Patients treated with rivaroxaban had similar rates of clot recurrence as patients treated with warfarin. But they had a lower rate of bleeding, with nearly half as many major bleeds as patients taking warfarin, according to the trial results presented at the American College of Cardiology meeting in Chicago.

Bueller said rivaroxaban may soon replace warfarin in treating venous blood clots because it’s easier to manage and appears to be safer.

“In those patients where we use warfarin today, we will gradually see replacement by these new anti-coagulants,” he said.

Copyright 2012 ABC News Radio


Study: New Drug May Prevent Stroke Better Than Aspirin

Photo Courtesy - Getty Images(ONTARIO, Canada) -- Patients at risk for strokes from blood clots who take aspirin because they can't take strong blood thinning drugs like warfarin may benefit significantly from a new drug, according to a new study presented at an American Stroke Association meeting in Canada.

The study's authors compared a new blood thinning drug, apixaban, to aspirin in 5,600 patients with atrial fibrillation -- an abnormal heart beat that can increase a person’s risk of stroke from blood clots -- who could not take warfarin.  Over a period of about one year, they found that 1.6 percent of those taking apixaban suffered a stroke compared to 3.6 percent of those taking aspirin.

The findings were considered so significant that the study was stopped early.

Additionally, apixaban was just as safe as aspirin in these patients, with major bleeding events in each group being 1.4 percent and 1.2 percent for apixaban and aspirin, respectively.

Copyright 2011 ABC News Radio

ABC News Radio