(NEW YORK) -- Peyton Manning will take on Tom Brady for the 14th time when the Denver Broncos take on the Patriots in New England on Sunday night.
Denver is coming off handing the Chiefs their first loss of the season and Manning is looking forward to the challenge of facing a Bill Belichick led defense.
"It's pretty well documented my respect for Tom as a quarterback," Manning said this week. "The way he prepares. The way he's better each season than the year before. Those are the couple of the many things that are impressive about him as a quarterback."
Manning could be without Wes Welker, who is a gametime decision after suffering a concussion in the win over the Chiefs.
"I want to be out there," Welker, who practiced on Thursday for the first time all week. "I mean, there are not too many games I've missed in my whole career and I love playing the game, especially in big atmospheres like this. So, I'm doing everything possible in my power to make sure that I get the opportunity to play in a game like this."
Welker spent the last five seasons in New England with Brady.
"(Welker is) a tough guy so he's played through everything," Brady said. "This is a big game for both teams so you have to expect their best players. I'm sure all those guys will be ready to go."
Brady and the Patriots got the best of Manning last year 31-21 in New England.
Copyright 2013 ABC News Radio