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Syracuse Hands No. 9 Louisville First Loss

Streeter Lecka/Getty Images(SYRACUSE) -- Ninth-ranked Lousiville came into Saturday's game agains the Syracuse Orange at the Carrier Dome with hopes of continuing a perfect season. The hosts would have none of it.

Ryan Nassib threw for three touchdowns and the Orange forced two Cardinals turnovers in a 45-26 rout that gave Louisville its first loss of the season and ruined whatever BCS Championship aspirations the Cardinals had.

Syraucse (5-5) ballooned a close game into a blowout in the second quarter where they scored 21 staight points to go ahead 31-10. The Orange had 339 yards of total offense in the first half alone and never looked back.

Nassib completed 15 of 23 passes for 246 yards and three scoring tosses to lead Syracuse.

For Louisville (9-1), it was a struggle to defend the Orange and fell into second place in the Big East. Quarterback Teddy Bridgewater threw for 424 yards and three touchdowns, but the Cardinals only managed 48 rushing yards compared to 278 on the ground for Syracuse.

Syracuse needs just one more win to become bowl eligible, and play their remaining two games on the road. 

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